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Antibody diversity is produced by

A. V(D)J recombination.

B. imprecise end joining during V(D)J recombination.

C. somatic hypermutation.

D. all of the above.

User Tobsecret
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1 Answer

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Final answer:

Antibody diversity is produced by V(D)J recombination, imprecise end joining during V(D)J recombination, and somatic hypermutation, which all contribute to a vast array of unique antibodies capable of responding to various antigens.

Step-by-step explanation:

Antibody diversity is produced by V(D)J recombination, imprecise end joining during V(D)J recombination, and somatic hypermutation. During the maturation of germ-line B cells, DNA recombinase facilitates the random excision and splicing of variable (V), diversity (D), and joining (J) gene segments to form a myriad of unique V-D-J combinations that contribute to the variable region of antibodies. These recombination events, along with subsequent somatic hypermutations which further diversify the antibodies' antigen-binding sites, ensure our immune system can recognize and respond to a vast array of foreign antigens.

User Milan Gajera
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8.1k points
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