Question

Which of the following can bind to ncRNAs?

A) DNA

B) RNA

C) Proteins

D) Small molecules

E) All of the above

Answer 1

ncRNAs can bind with DNA, RNA, proteins, and small molecules, indicating that all of the above are correct choices for what can interact with non-coding RNAs.

Step-by-step explanation:

Non-coding RNAs (ncRNAs) can interact with various types of molecules. DNA can interact with ncRNAs especially in the context of chromatin remodeling and epigenetic modifications. RNA molecules can also bind to ncRNAs to form double-stranded structures, such as in the case of miRNA or siRNA, which play roles in RNA interference mechanisms. Proteins, particularly RNA-binding proteins (RBPs), can recognize and bind to specific sequences or structures in ncRNAs, influencing their stability, localization, and function. Finally, small molecules, which include a variety of compounds, can interact with ncRNAs, often affecting their structure and function, like in riboswitches found in some mRNAs. Therefore, the answer to the question is E) All of the above. Each of these entities can form complexes with ncRNAs, contributing to the diverse regulatory functions these RNAs perform within the cell.