Question

T/F The general transcription factors that assemble at a eukaryotic promoter are different, depending on the specific gene being transcribed by polymerase II.

Answer 1

The general transcription factors for RNA polymerase II transcription in eukaryotes are consistent across different genes and not unique to each, making the statement false.

Step-by-step explanation:

The answer to the question is false. The general transcription factors that assemble at a eukaryotic promoter for the initiation of transcription by RNA polymerase II are not different depending on the specific gene being transcribed. These factors, known collectively as the basal transcription factors, are denoted by TFII and include subsets such as TFIID which contains the TATA-binding protein (TBP). These factors are universally required for the transcription of all protein-coding genes by RNA polymerase II, regardless of the gene being transcribed. Therefore, they are consistent across different genes rather than being unique to each.