Question

Which of the following steps in DNA mismatch repair occurs FIRST?

(A) DNA ligase joins the strand
(B) Mismatch repair proteins recognize and bind to the mismatch
(C) A region of the new strand is removed
(D) A new section of DNA is synthesized by DNA polymerase

Answer 1

In DNA mismatch repair, the initial step is the recognition and binding of the mismatch repair proteins to the mismatch on the DNA strand

Step-by-step explanation:

The first step in DNA mismatch repair is when mismatch repair proteins recognize and bind to the mismatch. These proteins are pivotal in identifying the sites of errors made during DNA replication. After the mismatch is identified, the repair mechanism involves a series of steps where the newly synthesized, erroneous strand is removed by nuclease action, followed by resynthesis using DNA polymerase, and finally, the strand is rejoined by DNA ligase.