Final answer:
Nonhomologous end joining does not ensure a high degree of fidelity to the original DNA sequence when repairing DNA double-strand breaks.
Step-by-step explanation:
False. Nonhomologous end joining is a mechanism that repairs DNA double-strand breaks, but it does not ensure a high degree of fidelity to the original DNA sequence. Nonhomologous end joining involves removing damaged and adjacent DNA and rejoining the cut ends, which can sometimes result in deletions or insertions. It is considered an error-prone repair mechanism.