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Before DNA polymerase can begin DNA replication, primase must synthesize what?

(A) An RNA primer
(B) A DNA primer
(C) Telomere repeats
(D) All of the above

1 Answer

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Final answer:

Primase synthesizes an RNA primer which is essential for DNA polymerase to begin DNA replication.

Step-by-step explanation:

Before DNA polymerase can begin the process of DNA replication, primase must synthesize an RNA primer. This is necessary because DNA polymerases require a pre-existing 3'-OH end to which they can add nucleotides. The RNA primer created by primase provides this starting point. The primer is a short sequence of RNA nucleotides that is complementary to the DNA template strand. Once in place, DNA polymerase extends the RNA primer, adding DNA nucleotides to synthesize the new strand.

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