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Okazaki fragments

(A) Occur on the leading strand
(B) Do not require primers
(C) Are joined by DNA ligase
(D) All of the above

1 Answer

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Final answer:

Okazaki fragments are short DNA sequences synthesized on the lagging strand during DNA replication, requiring primers and joined by DNA ligase.

Step-by-step explanation:

Okazaki fragments are essential components of DNA replication, particularly on the lagging strand. They are short stretches of DNA that are synthesized away from the replication fork. Each of these fragments requires a primer to begin synthesis, which is later removed and filled with DNA nucleotides. Once synthesized, the Okazaki fragments are joined together by the enzyme DNA ligase, which creates a continuous DNA strand by forming covalent bonds between the adjacent DNA fragments. During replication, the lagging strand is formed in a discontinuous manner, opposite to the continuous synthesis of the leading strand. Therefore, the correct answer to the question is that Okazaki fragments (C) Are joined by DNA ligase.

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