Final answer:
The statement is true; DNA polymerase will switch the new DNA strand to a separate active site for proofreading to correct any misincorporated nucleotides during DNA replication.
Step-by-step explanation:
The statement that the new DNA strand will switch from one active site on the polymerase to another for proofreading is true. During DNA replication, DNA polymerase carries out a vital proofreading function to ensure the accuracy of DNA synthesis. If DNA polymerase identifies an incorrectly paired nucleotide, it will switch the DNA strand to its 3' exonuclease active site. This action allows the enzyme to remove the incorrectly added nucleotide. After excision, the polymerase can then insert the correct nucleotide. This proofreading ability of DNA polymerase enhances the fidelity of DNA replication, greatly reducing the rate of errors and mutations.