Question

What was the effect of TSH injections on the hypophysectomized rat's BMR? How does the BMR in this case compare with the normal rat's BMR? Was the dose of TSH in the syringe too large, too small, or just right?

Answer 1

The effect of TSH injections on a hypophysectomized rat's BMR is to increase it. However, the dosage of TSH in the syringe must be appropriate to avoid any detrimental effects.

Step-by-step explanation:

The BMR (Basal Metabolic Rate) of a hypophysectomized rat is significantly lower than a normal rat's BMR. This is because the hypophysectomized rat lacks a pituitary gland, which is responsible for producing thyroid-stimulating hormone (TSH), which in turn stimulates the release of thyroid hormones, such as thyroxine (T4) and triiodothyronine (T3). Without TSH, the hypophysectomized rat's thyroid hormones are not produced in adequate amounts, resulting in a lower BMR.

The injection of TSH into the hypophysectomized rat would likely increase its BMR, as TSH stimulates the production of thyroid hormones. However, the effectiveness of the dose of TSH in the syringe would depend on the specific dosage given. If the dosage was too large, it could result in an excessive increase in the rat's BMR, leading to hyperthyroidism. On the other hand, if the dosage was too small, it may not have a significant effect on the rat's BMR.