Final Answer:
The statement given "FEN1 is an exo-/endonuclease that recognizes the structure created when one strand of DNA is displaced from a duplex as a "flap."" is true. Option A is answer.
Step-by-step explanation:
FEN1, or Flap Endonuclease 1, plays a crucial role in DNA replication and repair. It possesses both exo- and endonuclease activities. In DNA replication, when the synthesis of the lagging strand generates a flap—a protruding single-stranded DNA segment—FEN1 recognizes this structure.
FEN1 then cleaves the flap, ensuring accurate processing of Okazaki fragments during DNA replication. Its endonuclease activity enables it to make incisions in the DNA structure, and the exo-activity allows it to remove the protruding flap. Thus, the statement is true, as FEN1 is specialized in recognizing and processing flaps during DNA processing.
Option A is answer.
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Complete Question
FEN1 is an exo-/endonuclease that recognizes the structure created when one strand of DNA is displaced from a duplex as a "flap."
True
False
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