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Define a maternal tumor resulting from abnormal fetal tissue from the placental implantation site, characterized by the absence of villi and proliferation of cytotrophoblasts.

User Pi Horse
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Final answer:

A maternal tumor resulting from abnormal fetal tissue from the placental implantation site is called a choriocarcinoma. It is characterized by the absence of villi and the proliferation of cytotrophoblasts.

Step-by-step explanation:

A maternal tumor resulting from abnormal fetal tissue from the placental implantation site is known as a choriocarcinoma. In this condition, the tumor originates from the trophoblast cells, specifically the cytotrophoblast cells. Choriocarcinoma is characterized by the absence of villi and the proliferation of cytotrophoblasts.

Choriocarcinoma is a malignant and aggressive form of trophoblastic disease.

Key features of choriocarcinoma include:

Origin:

Arises from trophoblastic cells, specifically the chorionic tissue.

Histology:

Characterized by the presence of syncytiotrophoblasts and cytotrophoblasts.

There is a rapid and abnormal proliferation of these trophoblastic cells.

Invasiveness:

Choriocarcinoma is highly invasive and has the potential to spread (metastasize) quickly to other organs, such as the lungs, liver, and brain.

Clinical Features:

Presents with abnormal vaginal bleeding, an enlarged uterus, and other symptoms related to metastasis.

Choriocarcinoma can occur following a complete hydatidiform mole (molar pregnancy), a normal pregnancy, or even a miscarriage.

Diagnosis:

Diagnosis is typically confirmed through histological examination of biopsy samples obtained during a dilation and curettage (D&C) procedure.

Treatment:

Choriocarcinoma is a highly treatable but aggressive malignancy.

Treatment often involves a combination of surgery (such as hysterectomy), chemotherapy, and sometimes radiation therapy.

Chemotherapy is particularly effective in treating choriocarcinoma, and multiple agents may be used.

Prognosis:

With prompt and appropriate treatment, the prognosis for choriocarcinoma is generally favorable, and many patients achieve a complete cure.

Choriocarcinoma is a rare condition, and its management is typically coordinated by a specialized healthcare team that may include gynecologic oncologists and other specialists. If you suspect or have been diagnosed with choriocarcinoma, it's crucial to consult with a healthcare professional for a thorough evaluation and appropriate treatment plan.

User Brian Jorgensen
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