Question

Evaluate the statements below and determine which is the best reason for why eukaryotes use basal transcription factors?

-RNA Polymerase cannot bind to the DNA without their aid
-They interact with coactivators
-They give the cell tight control over transcription
-Eukaryotes do not use the sigma factor
-They allow RNA Polymerse to locate the promoter

Answer 1

Eukaryotes use basal transcription factors because they are essential for the formation of a preinitiation complex that recruits RNA Polymerase II, which cannot bind to the DNA on its own. This ensures meticulous regulation of transcription and gene expression.

Step-by-step explanation:

The best reason for why eukaryotes use basal transcription factors is that RNA Polymerase cannot bind to the DNA without their aid. In eukaryotic cells, transcription requires more than just RNA polymerase; a variety of proteins known as transcription factors must first bind to the promoter region to initiate the complex process of transcription. Basal transcription factors are part of this process, forming a preinitiation complex that recruits RNA polymerase II, which is essential for the synthesis of mRNA. This system ensures that transcription is tightly regulated and that the cell produces the necessary pre-mRNAs for protein synthesis.