Final answer:
Single-strand binding proteins form complexes that cover 35 to 65 nucleotides on the single-stranded DNA during replication, preventing the strands from prematurely re-annealing.
Step-by-step explanation:
Single-strand binding proteins form complexes on separated DNA strands during replication. Each protein complex covers from 35 to 65 nucleotides to protect the single-stranded DNA and prevent it from reforming into a double helix prematurely. This is essential during DNA replication to ensure that the single strands remain apart so that the new daughter strands can be synthesized accurately.