Final Answer:
The statement given "All DNA polymerases rquire a nucleotide with a 3-OH group to which a new nucleotide can be added. Because of this requirement DNA polymerases cannot initiate DNA synthesis on a bare template, rather they require an existing 3-0H group to get started." is true. Option A is answer.
Step-by-step explanation:
DNA polymerases are enzymes responsible for synthesizing DNA strands during replication. They function by adding nucleotides to the 3-OH group of the growing DNA chain. The 3-OH group serves as the site for the attachment of a new nucleotide, forming the phosphodiester bond in the DNA backbone. DNA polymerases cannot initiate DNA synthesis on a bare template; instead, they require a primer with an existing 3-OH group.
This requirement for a 3-OH group is crucial for the fidelity of DNA replication, ensuring that nucleotides are added in the correct order. The statement accurately reflects the essential role of the 3-OH group in the initiation of DNA synthesis.
Option A is answer.
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Complete Question
All DNA polymerases rquire a nucleotide with a 3-OH group to which a new nucleotide can be added. Because of this requirement DNA polymerases cannot initiate DNA synthesis on a bare template, rather they require an existing 3-0H group to get started.
a). True
b). False
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