Final answer:
Expanding nucleotide repeats can lead to diseases that become more severe in each generation, a process known as anticipation. This is often seen in diseases caused by trinucleotide repeat expansions, such as Huntington's disease.
Step-by-step explanation:
Expanding nucleotide repeats can lead to diseases that become more severe in each generation, a process known as anticipation. Anticipation refers to the phenomenon where the symptoms of a genetic disorder become more pronounced or appear at an earlier age with each successive generation. This is often seen in diseases caused by trinucleotide repeat expansions, such as Huntington's disease.