Question

Crohn's disease 1. Location 2. Characteristics on a radiograph 3. Other structural characteristics 4. List outcomes of severe inflammation

A) A) 1: Colon; 2: String sign, cobblestone appearance; 3: Skip lesions, transmural involvement; 4: Malabsorption, strictures
B) A) 1: Small intestine; 2: Lead-pipe appearance; 3: Mucosal involvement only; 4: Hyperplasia, hypertrophy
C) A) 1: Esophagus; 2: Barrett's esophagus; 3: Linear ulcers; 4: Atelectasis, fibrosis
D) A) 1: Stomach; 2: Punched-out ulcers; 3: Submucosal involvement; 4: Hyponatremia, hypokalemia

Answer 1

Crohn's disease is an inflammatory bowel disease that can affect any part of the GI tract. It is characterized by a cobblestone appearance and string sign on a radiograph. Severe inflammation can lead to malabsorption and strictures.

Step-by-step explanation:

Crohn's disease is a type of inflammatory bowel disease that can affect any part of the gastrointestinal (GI) tract from the mouth to the anus. It most commonly affects the ileum, which is the final part of the small intestine. On a radiograph, Crohn's disease can be characterized by a cobblestone appearance and string sign, indicating transmural involvement and skip lesions. Other structural characteristics of Crohn's disease include strictures and malabsorption due to faulty nutrient absorption.

Severe inflammation in Crohn's disease can lead to various outcomes, including malabsorption and strictures. Malabsorption occurs due to the impaired absorption of nutrients in the inflamed GI tract. Strictures refer to narrowed areas of the intestines that can lead to bowel obstruction.