Final answer:
Inhibition of receptor-mediated endocytosis can lead to hypercholesterolemia by preventing the clearance of LDL cholesterol from the blood, as in the case of familial hypercholesterolemia.
Step-by-step explanation:
Inhibition of receptor-mediated endocytosis could induce hypercholesteremia as stated in Option A. Receptor-mediated endocytosis is essential for the removal of specific substances, such as low-density lipoprotein (LDL), from the blood. In familial hypercholesterolemia, a condition characterized by defective or missing LDL receptors, individuals can have dangerously high levels of cholesterol due to their cells' inability to clear LDL from the blood. The failure of this process does not directly relate to the mechanisms that lead to diabetes mellitus; instead, resistance to insulin, not cholesterol uptake issues, is a primary cause for this condition.