Final answer:
Chromosomal incompatibilities are intrinsic factors that can lead to inherited disorders, such as abnormalities in chromosome number and chromosomal structural rearrangements. Aberrations in sex chromosomes typically have milder phenotypic effects compared to aneuploidies. Inversions and translocations, which rearrange chromosome structures, can reduce fertility due to the likelihood of nondisjunction during meiosis.
Step-by-step explanation:
Chromosomal incompatibilities can be considered as intrinsic factors. Inherited disorders such as abnormalities in chromosome number and chromosomal structural rearrangements can arise due to abnormal behavior of chromosomes during meiosis. These abnormalities can result in problematic phenotypic effects, and even small segments of chromosomes can span many genes, making chromosomal disorders dramatic and often fatal. Aberrations in sex chromosomes typically have milder phenotypic effects compared to aneuploidies. Additionally, inversions and translocations, which rearrange chromosome structures, can reduce fertility due to the likelihood of nondisjunction during meiosis.