Final Answer:
The most appropriate treatment for confluent and reticulated papillomatosis is Oral retinoids. Thus the correct option is (D).
Step-by-step explanation:
Confluent and reticulated papillomatosis (CRP) is a dermatological condition that often responds well to oral retinoids. This class of medications includes isotretinoin, which has shown efficacy in treating CRP by regulating keratinization and reducing hyperpigmentation associated with the condition1. The use of oral retinoids addresses the underlying pathophysiology, making it a targeted and effective treatment option.Thus the correct option is (D).
Oral retinoids work by normalizing follicular keratinization, preventing the formation of hyperkeratotic papules, and reducing pigmentation2. Isotretinoin, a commonly prescribed oral retinoid, is generally administered at a dose of 0.5 to 1 mg/kg/day for several weeks3. Monitoring for potential side effects, such as mucocutaneous dryness and elevated liver enzymes, is essential during treatment. Dermatologists may adjust the dosage based on the patient's response and tolerance, ensuring optimal therapeutic outcomes.
In conclusion, while topical antifungals, topical steroids, and oral antibiotics may be considered for other dermatological conditions, oral retinoids, specifically isotretinoin, stand out as the preferred treatment for confluent and reticulated papillomatosis due to their targeted mechanism of action and proven efficacy in managing the condition. Footnotes
Scheinfeld N. Confluent and reticulated papillomatosis: a review of the literature. Am J Clin Dermatol. 2006;7(5):305-313. ↩
Habif TP. Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 6th ed. Edinburgh: Mosby Elsevier; 2016. ↩
Layton A. The use of isotretinoin in acne. Dermatoendocrinol. 2009;1(3):162-169. ↩