Question

What disease presents as yellow-brown papules, preference for flexures, can involve oral mucosa and eyes. Also is associated with diabetes insipidus (thirst and increased urination)

A) Xanthoma disseminatum
B) Eruptive xanthomas
C) Necrobiotic xanthogranuloma
D) Juvenile xanthogranuloma

Answer 1

Xanthoma disseminatum presents with yellow-brown papules, typically occurring in skin folds, that may also affect the oral mucosa and eyes, and can be associated with diabetes insipidus.

Step-by-step explanation:

The disease that presents as yellow-brown papules, preference for flexures, can involve oral mucosa and eyes, and is associated with diabetes insipidus (thirst and increased urination) is A) Xanthoma disseminatum. This condition is characterized by the presence of numerous yellowish to brownish papules on the skin, especially in areas such as the folds of the skin. The association with diabetes insipidus is a key feature of this condition. Xanthoma disseminatum is a non-X histiocytosis that affects multiple systems and can have various other manifestations along with the skin symptoms, including involvement of the mucous membranes and the eyes.