Question

Compared to studying muscle function in vivo, using an isolated single muscle fiber to study muscle fatigue provides which of the following advantages?

a. measurements of ions and metabolites within fiber possible
b. Both measurements of ions and metabolites within fiber possible and force production of the single fiber can be measured are correct
c. force production of the single fiber can be measured
d. environment identical to in vivo conditions

Answer 1

Studying muscle fatigue using an isolated single muscle fiber allows for measurements of ions and metabolites and force production, which can provide a deeper understanding of muscle function.

Step-by-step explanation:

Compared to studying muscle function in vivo, using an isolated single muscle fiber to study muscle fatigue provides the advantages of both measurements of ions and metabolites within the fiber being possible and the ability to measure force production of the single fiber. In vivo conditions provide a complex environment that can make it difficult to measure these factors directly. However, the environment of an isolated muscle fiber does not completely replicate in vivo conditions; it allows for more controlled experiments where specific variables can be manipulated and observed in isolation.

Answer 2

Compared to studying muscle function in vivo, using an isolated single muscle fiber to study muscle fatigue provides the advantages that ` Both measurements of ions and metabolites within fiber possible and force production of the single fiber can be measured are correct`

Therefore, the correct answer is b

Step-by-step explanation:

Studying muscle function in vivo involves studying muscle activity within a living organism. While this approach provides valuable insights, it can be challenging to directly measure certain parameters within the muscle fiber. On the other hand, using an isolated single muscle fiber allows for more precise measurements and control over the experimental conditions.

One advantage of studying muscle fatigue in an isolated single muscle fiber is the ability to measure ions and metabolites within the fiber. By directly accessing the fiber, researchers can analyze the concentration of ions such as calcium and metabolites such as ATP and lactate. These measurements provide valuable information about the biochemical changes that occur during muscle fatigue.

Additionally, studying an isolated single muscle fiber allows for the measurement of force production. Researchers can attach the fiber to a force transducer and measure the force generated by the muscle fiber under different conditions. This provides insights into the contractile properties and fatigue characteristics of the muscle fiber.

While the environment may not be identical to in vivo conditions, studying an isolated single muscle fiber still provides valuable advantages in terms of measuring ions, metabolites, and force production.

Therefore, the correct answer is b. Both measurements of ions and metabolites within the fiber possible and force production of the single fiber can be measured are correct.