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True or false:

The addition of the poly A tail to a eukaryotic mRNA requires a series of Ts in the corresponding regions of the DNA.

User TC Zhang
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Final answer:

The addition of the poly A tail to a eukaryotic mRNA does not require a series of Ts in the corresponding regions of the DNA.

Step-by-step explanation:

True or false: The addition of the poly A tail to a eukaryotic mRNA requires a series of Ts in the corresponding regions of the DNA.



The statement is false.



The addition of the poly A tail to a eukaryotic mRNA does not require a series of Ts in the corresponding regions of the DNA. Instead, the poly(A) polymerase recognizes a specific sequence near the 3' end of the mRNA. This sequence is known as the AAUAAA consensus sequence, and it is located in the pre-mRNA. Once elongation is complete, an enzyme called poly-A polymerase adds a string of approximately 200 adenine residues, called the poly-A tail, to the 3' end of the mRNA. This modification protects the mRNA from degradation and signals to cellular factors that the transcript needs to be exported to the cytoplasm.

User Zara
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