Question

During the elongation phase of protein synthesis, an antibiotic inbitor blocks protein synthesis by inhibiting the peppily transferase reaction from occurring. At the inhibited ribosome, the A-site is occupied by

A. Aminoacyl tRNA
B. Peptidyl RNA
C. Empty tRNA
D. ATP
E. Nothing

Answer 1

Tetracycline blocks the attachment of aminoacyl-tRNA to the ribosome, inhibiting the growth of the protein chain. Chloramphenicol blocks peptidyl transfer, also preventing the growth of the protein chain.

Step-by-step explanation:

Tetracycline, a type of antibiotic, blocks the A site on the bacterial ribosome, preventing the attachment of aminoacyl-tRNA to the ribosome. This inhibition prevents the growth of the protein chain since the amino acids cannot be added to the growing polypeptide chain. Chloramphenicol, another antibiotic, blocks peptidyl transfer, which is the formation of peptide bonds between amino acids. Therefore, chloramphenicol would also prevent the growth of the protein chain.