Question

True or false:

Eukaryotic RNA polymerases (like RNA polymerase II) are regulated by sigma factors.

Answer 1

False. Eukaryotic RNA polymerases, such as RNA polymerase II, are not regulated by sigma factors. Transcription initiation in eukaryotes is controlled by different types of transcription factors.

Step-by-step explanation:

False. Eukaryotic RNA polymerases, including RNA polymerase II, are not regulated by sigma factors. In prokaryotes, sigma factors play a crucial role in guiding RNA polymerase to specific promoters and initiating transcription. However, in eukaryotes, transcription initiation is regulated by different types of transcription factors. General (or basal) transcription factors bind to the core promoter region to assist with RNA polymerase binding, while specific transcription factors bind to other regions outside of the core promoter to enhance or repress polymerase activity.