Question

36. Which of the following statements regarding membrane proteins is FALSE?

(a) Integral membrane proteins often precipitate (form insoluble aggregates) in aqueous solutions lacking detergents.
(b) Some hydrophobic amino acids in membrane proteins are not in contact with the lipid bilayer.
(c) Peripheral membrane proteins can be dissociated from membranes using a gentle detergent.
(d) Strong detergents can completely unfold both membrane and nonmembrane proteins.
(e) In transmembrane proteins that form an aqueous pore through the membrane, the pore is lined with hydrophobic amino acid side chains

Answer 1

The FALSE statement regarding membrane proteins is that in transmembrane proteins that form an aqueous pore through the membrane, the pore is lined with hydrophobic amino acid side chains.

Step-by-step explanation:

The statement that is FALSE regarding membrane proteins is (e) In transmembrane proteins that form an aqueous pore through the membrane, the pore is lined with hydrophobic amino acid side chains.

Transmembrane proteins that form a pore through the membrane typically have polar or charged amino acid side chains lining the pore to allow the passage of polar molecules and ions.

The other statements are true. (a) Integral membrane proteins often precipitate in aqueous solutions lacking detergents; (b) Some hydrophobic amino acids in membrane proteins are not in contact with the lipid bilayer; (c) Peripheral membrane proteins can be dissociated from membranes using a gentle detergent; (d) Strong detergents can completely unfold both membrane and nonmembrane proteins.