Question

HIV+ patient with EBV PCR+ CSF:

a) HIV encephalopathy; HAART therapy
b) Primary CNS lymphoma; Chemotherapy
c) Cryptococcal meningitis; Antifungal therapy
d) Progressive multifocal leukoencephalopathy; Antiviral therapy

Answer 1

The most likely cause of a positive EBV PCR test in an HIV+ patient with CSF is primary CNS lymphoma, which should be treated with chemotherapy(option b).

Step-by-step explanation:

When an HIV+ patient has a positive CSF PCR test for Epstein-Barr virus (EBV), the most likely cause is primary CNS lymphoma. Primary CNS lymphoma is a type of non-Hodgkin lymphoma that affects the central nervous system, and it is more common in immunocompromised individuals, such as those with HIV.

The appropriate treatment for primary CNS lymphoma is chemotherapy. Antiviral therapy, such as HAART therapy for HIV, would not be effective in treating primary CNS lymphoma.Therefore , the correct answer is b) Primary CNS lymphoma; Chemotherapy.