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Which of the following statements about calcium ions is true?

Ca2+ enters cells through Ca2+ channels that can be voltage-, ligand- or mechanically-gated.

Most intracellular Ca2+ is stored within the nucleus.

Ca2+ binds to the protein calmodulin.

Ca2+ binding to the regulatory protein troponin initiates muscle relaxation.

Ca2+ binding to regulatory proteins triggers endocytosis of secretory vesicles.

The Ca2+ concentration is higher in the ECF compared with the ICF.

User Amateur
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Final answer:

Calcium ions (Ca2+) enter cells through various gated channels and bind to proteins like calmodulin and troponin, triggering physiological responses such as muscle contractions. Highest Ca2+ concentrations are present in the extracellular fluid. Ca2+ plays a versatile role in cellular processes.

Step-by-step explanation:

Among the statements provided about calcium ions (Ca2+), there are certain true aspects relevant to Ca2+ physiological roles and mechanisms in the cell:

Ca2+ enters cells through Ca2+ channels that can be voltage-, ligand-, or mechanically-gated.

Ca2+ binds to the protein calmodulin.

Most intracellular Ca2+ is stored within cytoplasmic compartments such as the sarcoplasmic or endoplasmic reticulum, not the nucleus.

Ca2+ binding to the regulatory protein troponin initiates muscle contraction, not relaxation.

Ca2+ concentration is higher in the extracellular fluid (ECF) compared with the intracellular fluid (ICF).

The exchange of Ca2+ through cellular mechanisms is crucial for various cellular processes, including muscle contractions and neurotransmitter release at synapses. The role of Ca2+ is multifaceted, depending on the cell type and context within the physiological processes.

User Slanden
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