Final answer:
A holosystolic murmur at the apex radiating to the back and clavicles is indicative of mitral regurgitation.
Step-by-step explanation:
A holosystolic murmur at the apex that radiates to the back and clavicles is indicative of mitral regurgitation.
During the cardiac cycle, the mitral valve, which separates the left atrium from the left ventricle, fails to close properly, causing blood to flow back into the left atrium from the left ventricle. This backward flow of blood creates the murmur sound. This condition is also known as mitral insufficiency. The murmur is heard throughout the entire systole phase of the cardiac cycle and typically has a blowing quality.
To differentiate between the given options, it is important to understand the location of the murmur and the direction in which it radiates. In this case, the murmur is at the apex and radiates to the back and clavicles, which is characteristic of mitral regurgitation.