Final answer:
The deviations with pathology/exercise relevant to cardiomyocytes are increased oxygen delivery, which reflects a heightened need, and decreased ATP production, which occurs due to impaired oxygen supply during ischemic conditions.
Step-by-step explanation:
The question asks about two deviations with pathology/exercise to cardiomyocytes and the options provided revolve around oxygen delivery, ATP production, and calcium release in the context of cardiac muscle physiology. Cardiomyocytes rely heavily on aerobic respiration to metabolize lipids and carbohydrates, with a high demand for oxygen to synthesize ATP required for their contraction cycles. During pathological conditions such as ischemia, oxygen delivery is compromised, leading to decreased ATP production, and calcium may be excessively released from the endoplasmic reticulum or mitochondria into the cytoplasm, increasing cytoplasmic calcium concentration.
When considering both the normal physiology of cardiomyocytes and what happens under pathologic conditions, the correct answer to the student's question would be option A) Increased oxygen delivery, decreased ATP production. This reflects the ischemic condition where despite an increased need for oxygen, the actual delivery to the cardiomyocytes is impaired. The second part of the option, decreased ATP production, is a direct consequence of the reduced oxygen supply impacting aerobic metabolism.