Final answer:
In Canine atopic dermatitis during the subacute/chronic phase, prolonged inflammation and pruritus are typical symptoms, reflecting an ongoing immune response similar to delayed hypersensitivity in humans.
Step-by-step explanation:
During the subacute/chronic reaction in Canine atopic dermatitis, what is typically observed is prolonged inflammation and pruritus (C). This reflects a continued immune response where the skin does not return to a normal state. Instead, the animal experiences ongoing symptoms of atopic dermatitis, which can result in discomfort and the urge to scratch (pruritus). The condition is an immune response similar to delayed hypersensitivity in humans, where the T-helpers (TH1) cytokine-mediated inflammatory response is activated, leading to tissue damage. This is akin to reactions in humans such as the response to poison ivy or the tuberculosis skin test. Treatments including cortisone are utilized to suppress this response and reduce cytokine production, thereby alleviating symptoms.