Final answer:
Magnetic resonance imaging (MRI) is the most helpful study to differentiate a brachial plexus lesion from nerve root avulsion. Electromyography (EMG) and Nerve conduction study (NCS) can help diagnose nerve damage.
Step-by-step explanation:
The study that is most helpful differentiating a brachial plexus lesion from nerve root avulsion is Magnetic resonance imaging (MRI).
Electromyography (EMG) and Nerve conduction study (NCS) can help diagnose nerve damage, but they are not as useful in differentiating between a brachial plexus lesion and nerve root avulsion. Computed tomography (CT) scan is not typically used to evaluate brachial plexus lesions or nerve root avulsions.