Final answer:
Burkitt's lymphoma is caused by a chromosomal translocation involving the c-myc oncogene, leading to its overexpression and uncontrollable cell growth.
Step-by-step explanation:
Burkitt's lymphoma arises due to a chromosomal translocation involving the c-myc oncogene. Specifically, this translocation often occurs between chromosome 8, which houses the c-myc gene, and either chromosome 14, chromosome 2, or chromosome 22, involving the immunoglobulin heavy or light chain genes.
This translocation leads to the overexpression of the c-myc gene, which is a transcription factor crucial for cell growth. As a result, there is uncontrolled proliferation of B cells, subsequently forming tumors in the lymphatic system.