Question

TCA cycle inhibited by (three things) Stimulated by..

a) Inhibited by: ATP, NADH, Succinyl CoA; Stimulated by: ADP, NAD+, Calcium
b) Inhibited by: GTP, FADH2, Acetyl-CoA; Stimulated by: AMP, NADPH, Sodium
c) Inhibited by: Pyruvate, CoA, Citrate; Stimulated by: Oxygen, Glucose, Glutamate
d) Inhibited by: Malate, Isocitrate, Oxaloacetate; Stimulated by: Fructose, ATP, Carbon dioxide

Answer 1

The citric acid (TCA) cycle is inhibited by ATP, NADH, and Succinyl CoA and stimulated by ADP, NAD+, and Calcium. NADH inhibits several enzymes in the cycle, while ATP inhibits citrate synthase and a-ketoglutarate dehydrogenase. Calcium acts as a regulator and increases the reaction rate of many steps in the cycle.

Step-by-step explanation:

The citric acid cycle, also known as the TCA cycle or Krebs cycle, is inhibited by ATP, NADH, and Succinyl CoA. It is stimulated by ADP, NAD+, and Calcium. NADH inhibits several enzymes in the cycle, while ATP inhibits citrate synthase and a-ketoglutarate dehydrogenase. Calcium acts as a regulator and activates isocitrate dehydrogenase and a-ketoglutarate dehydrogenase, increasing the reaction rate.