Final answer:
Animal models for HD show that ASO treatment, such as antagonism of calcium-permeable AMPA receptors, could slow disease progression in humans.
Step-by-step explanation:
Animal models for HD (Huntington's disease) have been used to study the effectiveness of ASO (antisense oligonucleotide) treatment.
These animal studies, conducted on mouse and rat models, have shown promising results.
For example, a study conducted on knockout mice found that antagonism of calcium-permeable AMPA receptors could slow disease progression in HD.
These findings indicate the potential effectiveness of ASO treatment in humans with HD, although further research is needed for conclusive evidence.