Question

Complex of eIF-2, GTP and Met-tRNAiMet formed 2) this complex binds to 40S subunit:eIF-1A&eIF-3 complex, forms 43S pre initiation complex 3) mRNA& other factors add to form initiation complex --> GTP required! -- now scan to find AUG

a) Translation Initiation
b) Transcription Initiation
c) DNA Replication
d) RNA Splicing

Answer 1

In eukaryotes, translation initiation involves the formation of a complex called the initiation complex, which consists of mRNA, the 40S ribosomal subunit, eIFs, and GTP. The complex scans the mRNA until it finds the start codon AUG, forming the initiation complex. GTP is required for this process.

Step-by-step explanation:

In eukaryotes, translation initiation involves the formation of a complex called the initiation complex. This complex consists of mRNA, the 40S small ribosomal subunit, eukaryotic initiation factors (eIFs), and nucleoside triphosphates (GTP and ATP). The eIF-2 protein, when bound to GTP, brings the initiating met-tRNAi to the 40S ribosome. The complex scans along the mRNA until it finds the start codon AUG, where the initiation complex is formed. The large 60S ribosomal subunit then binds to complete the translation complex. GTP is required for this process.