Final answer:
To test for trinucleotide expansion diseases, factors such as identifying the specific repeat, determining the size of the expansion, and considering the inheritance pattern need to be taken into account.
Step-by-step explanation:
To test for trinucleotide expansion diseases, several factors must be taken into account. First, the specific trinucleotide repeat that is associated with the disease needs to be identified. This is done through genetic testing, which analyzes the DNA sequence to look for the presence of abnormal repeats. Second, the size of the repeat expansion needs to be determined, as larger expansions are generally associated with more severe symptoms. Finally, the inheritance pattern of the disease must be considered, as trinucleotide repeat expansions can be inherited in an autosomal dominant or autosomal recessive manner.