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How long does it take for initial HPV infection to progress to cancer?

User Angabriel
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Final answer:

The progression from initial HPV infection to cancer varies and can take many years, or even decades. High-risk strains like HPV 16 and HPV 18 may cause precancerous changes if the body fails to clear the infection, which can develop into cervical cancer.

Step-by-step explanation:

The progression from an initial HPV infection to cancer can vary greatly depending on the individual and the strain of the virus involved. High-risk HPV strains, particularly HPV 16 and HPV 18, are responsible for more than 70% of all cervical cancer cases. While the body can often clear HPV infections within 2 years, if a high-risk HPV infection persists, it may cause the cells of the cervix to develop precancerous changes. If not detected and treated, these changes can evolve into invasive cancer over time. The development process can span many years, or even decades, which underscores the importance of regular screening through Pap tests for women aged 21 to 65 and HPV tests for those aged 30 and older.

Development of Cervical Cancer

In the path from HPV to cancer, cells typically infected with the virus can heal on their own, but there are situations where the virus continues to spread and could potentially develop into invasive cancer. There is no single timeline for this progression, and it may not happen in all cases.

Preventive measures such as the HPV vaccine, sold under the name GARDASIL, are highly recommended and effective in preventing HPV infections. This vaccine is advised for girls and boys between the ages of 11 and 12, and for unvaccinated individuals up through age 21 for males and 26 for females, aiming to protect against HPV-related cancers later in life.

User Itsezc
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