Question

In the unfolded protein response, the accumulation of misfolded proteins in the ER serves as a signal for the cell to do which of the following?

Export the misfolded proteins to the cytosol
Glycosylate the misfolded protein
Produce more ER membrane and ER proteina

Answer 1

The accumulation of misfolded proteins in the ER serves as a signal for the cell to produce more ER membrane and ER protein.Produce more ER membrane and ER proteina

Step-by-step explanation:

In the unfolded protein response, the accumulation of misfolded proteins in the ER serves as a signal for the cell to produce more ER membrane and ER protein.

When proteins are synthesized in the rough endoplasmic reticulum (RER), they undergo modifications such as folding or the addition of sugars before being transported to their correct destinations. If these proteins are misfolded, it triggers a response called the unfolded protein response, where the cell increases the production of ER membrane and ER protein to handle the accumulating misfolded proteins.

For example, the cell may produce more chaperone proteins, which help in protein folding, or increase the size of the rough ER to accommodate the misfolded proteins.