Final answer:
A health risk of excessive cytokine release is severe tissue damage due to a cytokine storm, leading to systemic immune responses and potentially life-threatening conditions like septic shock.
Step-by-step explanation:
One health risk associated with excessive cytokine release is severe tissue damage. This phenomenon is known as a cytokine storm, where unregulated activation of T cells leads to life-threatening fever, inflammation, and shock. Pro-inflammatory cytokines like IL-1 and TNF-α play a part in this response.
At high concentrations, these cytokines can cause systemic immune responses that can be detrimental, such as vasodilation, edema, and drop in blood pressure leading to septic shock. The ensuing physiological responses can lead to multiple organ failure, emphasizing the critical need for prompt and targeted management to avert potentially fatal outcomes associated with cytokine storms.
These reactions can result in multiple organ failure and death if not managed rapidly.