Final answer:
Before initiating TCAs, checking vital signs is crucial because these drugs can lead to significant cardiovascular changes, like arrhythmias and blood pressure drops, which can be harmful, especially at the beginning of treatment. This monitoring is essential to patient safety and effective dose management.
Step-by-step explanation:
You should check vital signs before initiating administration of tricyclic antidepressants (TCAs) because these medications can cause significant changes in blood pressure and heart rate. Moreover, they can lead to cardiac arrhythmias and postural hypotension, which can be severe in some patients, especially when treatment is just starting. Monitoring vital signs helps ensure patient safety by allowing for the detection of any immediate adverse effects that may require medical intervention.
TCAs, such as imipramine, can have sedative effects which might increase the risk of falls or accidents, particularly in the elderly or in those with pre-existing health conditions. When given over time to patients with depression, TCAs can elevate mood, but at first, they might cause symptoms that are perceived as unpleasant, like light-headedness and a drop in blood pressure. Regularly checking vital signs can help in adjusting the dose appropriately and preventing complications related to these common side effects of TCAs.