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Moderna Vaccine Phase 1 Clinical Trials

a. What is the focus of Moderna Vaccine Phase 1 Clinical Trials?
b. Why is Phase 1 crucial in vaccine development?
c. How is the safety of the Moderna Vaccine assessed in Phase 1?
d. What are the key outcomes expected from Phase 1 Clinical Trials?

1 Answer

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Final answer:

Moderna Vaccine Phase 1 clinical trials focus on assessing safety and determining dosage range. Safety is assessed through monitoring for adverse reactions. Outcomes include establishing vaccine safety and evaluating pharmacokinetic properties.

Step-by-step explanation:

Phase 1 clinical trials of the Moderna Vaccine primarily focus on assessing its safety and tolerability in humans. These trials involve administering sub-therapeutic doses of the vaccine and gradually escalating to multiple dose studies. The goal is to determine the safe dosing range and whether the vaccine should progress to further development phases.

The safety of the Moderna Vaccine in Phase 1 is assessed by closely monitoring the participants for any adverse reactions or side effects. This includes recording data on any symptoms experienced and conducting regular physical examinations and laboratory tests.

The key outcomes expected from Phase 1 Clinical Trials include establishing the safety of the Moderna Vaccine, determining the appropriate dosage range, and evaluating its pharmacokinetic properties such as absorption and elimination.

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