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How does IFNy cause tissue damage in CD?

User Clweeks
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Final answer:

IFNy (interferon gamma) can cause tissue damage in CD (Crohn's disease) through its role in the immune response. This tissue damage can occur due to the activation of inflammatory cells and the release of chemicals like cytokines.

Step-by-step explanation:

IFNy (interferon gamma) can cause tissue damage in CD (Crohn's disease) through its role in the immune response. IFNy is a cytokine that is produced by immune cells and it helps in fighting against intracellular microbes. However, in conditions like CD, it can lead to tissue damage when it is overproduced or when the immune system becomes dysregulated. This tissue damage can occur due to the activation of inflammatory cells, such as macrophages, and the release of chemicals like cytokines, which cause inflammation and damage to the intestinal tissues.

User Noufal Kmc
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