Final answer:
The CXCR3 receptor is upregulated on enterocytes in CD, allowing the binding of chemokines and leading to inflammation and immune cell recruitment.
Step-by-step explanation:
The CXCR3 receptor is primarily expressed by immune cells, such as T cells and natural killer cells. In the context of CD, or Crohn's disease, it has been found that the CXCR3 receptor is upregulated on enterocytes, which are the cells lining the intestinal epithelium. In CD, the binding of chemokines, such as CXCL9 and CXCL10, to CXCR3 on enterocytes can lead to inflammation and recruitment of immune cells to the intestines.