Final answer:
In type 2 diabetes, target cells are resistant to insulin, whereas type 1 diabetes involves a lack of insulin production due to an autoimmune response.
Step-by-step explanation:
In type 2 diabetes, target cells do not respond normally to insulin. This condition is characterized by insulin resistance, where body cells are no longer sensitive to insulin. While the pancreas may still produce insulin, the cells of the body cannot use it efficiently, leading to elevated levels of blood glucose. In contrast, type 1 diabetes is primarily the result of the pancreas's inability to produce insulin due to the immune system attacking its insulin-producing beta cells.