Final answer:
The initiation of Positive Pressure Ventilation (PPV) in an infant with a heart rate less than 100, gasping, or apneic should be within 60 seconds of birth.
Step-by-step explanation:
In the context of newborn resuscitation, Positive Pressure Ventilation (PPV) should be initiated in an infant who has a heart rate less than 100, is gasping, or is apneic to normalize the heart rate and improve breathing. The goal is to start PPV within 60 seconds of birth, known as the 'Golden Minute'. This rapid response is critical as per the guidelines for newborn life support, indicating the urgency of establishing effective ventilation within this crucial time frame to reverse hypoxia and acidosis.