Final answer:
Protective or reverse isolation is necessary for transplant recipients, patients with severe burns, and individuals with leukemia, as they are all at high risk of infection due to compromised immune defenses or open wounds.
Step-by-step explanation:
Protective or reverse isolation is indicated in situations where patients are at high risk of infection due to compromised immune systems or open wounds. This includes transplant recipients, patients with severe burns, and individuals with leukemia who may have neutropenia as a result of their condition or treatment. Therefore, the answer is d. 1, 2, and 3.
Transplant recipients often require protective isolation to reduce the risk of infection while their immune system is suppressed by medications to prevent transplant rejection. Patients with burns may have compromised skin integrity, serving as a protective barrier against microbes and thereby necessitating reverse isolation. Individuals with leukemia, particularly those undergoing chemotherapy, may have low white blood cell counts, and thus, reverse isolation helps prevent infections.
Blood relatives are often preferred as organ donors because they are more likely to be compatible with the recipient, which can decrease the risk of organ rejection. Immunosuppression is critical in transplantation to reduce the recipient's immune response and prevent rejection of the transplanted organ or tissue.