Final answer:
The question pertains to vasoactive amines and the cell granule contents released by mast cells during an allergic or inflammatory response, specifically histamine, serotonin, prostaglandins, and leukotrienes.
Step-by-step explanation:
Vasoactive amines are crucial mediators in the body's allergic and inflammatory responses. When mast cells encounter an allergen to which they are sensitized, they undergo degranulation. This process releases cell granule contents into the surrounding tissue, which includes substances like histamine and serotonin. These components are crucial for initiating and propagating inflammatory signals in the body.
In addition to the preformed mediators like histamine and serotonin, the activated mast cells also synthesize new compounds such as prostaglandins and leukotrienes from membrane arachidonic acid metabolism. These substances have different roles in inflammation; for instance, prostaglandins are involved in increasing blood flow and causing pain, while leukotrienes attract neutrophils and increase permeability of blood vessels.