Final answer:
Pemphigus vulgaris is associated with Type II hypersensitivity and leads to the blistering of skin and mucous membranes (D). Other conditions under Type II hypersensitivity include Glomerulonephritis and Destruction of platelets, whereas Type III hypersensitivity is related to diseases like SLE, which may cause inflammation of the joints.
Step-by-step explanation:
Human antibody-mediated diseases such as Pemphigus vulgaris involve Type II hypersensitivity reactions. This particular type is characterized by the activity of IgG and IgM antibodies that bind to specific cellular antigens, leading to damage caused by an inflammatory response and cell lysis. For Pemphigus vulgaris, the answer to the question regarding its effect is D) Blistering of skin and mucous membranes. This disease results in the antibodies targeting the adhesion molecules in the skin, causing the blisters that are characteristic of this condition.
Other conditions associated with Type II hypersensitivity include Glomerulonephritis which can result from antibodies attacking the basement membranes in the kidneys (A), and the destruction of platelets commonly occurring in conditions like immune thrombocytopenic purpura (B). In contrast, Type III hypersensitivity involves immune complexes that can lead to systemic diseases, such as systemic lupus erythematosus (SLE), which may cause inflammation of the joints but is distinct from Type II hypersensitivity.