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Which class of drugs inhibits Dipeptidyl Peptidase-4 (DPP-4)?

a. Beta-blockers
b. ACE inhibitors
c. DPP-4 Inhibitors ²
d. Calcium channel blocker

1 Answer

3 votes

Final answer:

The DPP-4 inhibitors are the drug class that inhibits the DPP-4 enzyme, specifically designed to treat type 2 diabetes by increasing incretin levels and thus managing blood glucose levels.

Step-by-step explanation:

The class of drugs that inhibits Dipeptidyl Peptidase-4 (DPP-4) is appropriately named the DPP-4 inhibitors. They are a group of medications specifically designed to treat type 2 diabetes. By inhibiting the DPP-4 enzyme, they work to increase incretin levels (GLP-1 and GIP), which in turn inhibits glucagon release, increases insulin secretion, decreases gastric emptying, and decreases blood glucose levels.

The correct answer to the question is c. DPP-4 Inhibitors. Neither beta-blockers, ACE inhibitors, nor calcium channel blockers serve the function of inhibiting the DPP-4 enzyme. The provided references to other drug classes and their functions (blood pressure medication, classes of antipsychotics, etc.) are unrelated to the mechanism of action of DPP-4 inhibitors.

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