Question

What conditions result in decreased renal H+ excretion and decreased bicarbonate production?

Answer 1

Conditions that result in decreased renal H+ excretion and decreased bicarbonate production include the inhibition of carbonic anhydrase, excessive bicarbonate loss due to diarrhea, chronic adrenal insufficiency, renal damage, and elevated levels of ketones in unmanaged diabetes mellitus.

Step-by-step explanation:

Conditions that result in decreased renal H+ excretion and decreased bicarbonate production include:

1. Inhibition of carbonic anhydrase by certain diuretics.
2. Excessive bicarbonate loss due to diarrhea.
3. Chronic adrenal insufficiency, such as Addison's disease, which reduces aldosterone levels.
4. Renal damage, such as chronic nephritis.
5. Elevated levels of ketones in unmanaged diabetes mellitus, which binds bicarbonate in the filtrate and prevents its conservation.